Thumb-In-Motion is a one-handed Thumb-to-ring gesture interface to quickly access information without interfering with physical activity, such as running. The evaluation revealed that among the selected gestures, the tap, swipe-down, and swipe-left were the most ‘easy to use’. Interestingly, motion does not have a significant effect on the ease of use or on the execution time. However, interacting in motion was subjectively rated as more demanding. Finally, the gesture set was evaluated in real-world applications, while the user performed a running exercise and simultaneously controlled a lap timer, a distance counter, and a music player. This work was published at the Symposium on Spatial User Interaction (SUI ’18) in October 2018 in Berlin, Germany.